Tuesday, January 10, 2012

Shortage of naltrexone tablets

The American Society of Health-System Pharmacists reports a shortage of naltrexone tablets. This drug shortage is likely due to a shortage of the active principal ingredient, naltrexone hydrochloride. Covidien states that this is the reason they have the drug on back order, but Teva and Sandoz did not give a reason. This drug is used to combat alcohol and opioid drug addiction by combining with the receptors in the brain that are occupied by alcohol and opiates.

A question that arises is whether this shortage might be due, at least in part, to FDA approval of 50 mg tablets. Addicts seem to find this amount too high, and ask physicians for prescriptions from compounding pharmacies at a lower dose. Could that be how the active ingredient is being used instead of for the 50 mg tablets? Other addicts take the dubious route detailed on the Internet of obtaining a prescription for the 50 mg tablets, putting a tablet into suspension in distilled water, and gradually increasing their daily intake to combat their withdrawal symptoms.

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